Last Updated on February 8, 2025

Taking the Miami to Key West Drive is a must for anyone looking for an unforgettable trip. This journey is filled with stunning ocean views, charming coastal towns, and lots of attractions.
 
Whether you love adventure, nature, or family fun, this guide has you covered. We’ll show you 25 key stops that make the trip from Miami to Key West unforgettable. Get ready to find unique highlights and activities along the way!

Heading to the Florida Keys this year? 

 

Check out our must-have 7 day Florida Keys Itinerary!

 

Florida Keys Itinerary
A scenic view of the Shark Valley trail with sawgrass marshes and a blue sky at Everglades National Park

Essential Stop 1: Everglades National Park (Shark Valley)

Everglades National Park is a treasure of biodiversity and beauty. It’s home to a wide variety of wildlife. Shark Valley offers unique activities for a close-up look at the ecosystem.
 

Unique Wildlife Experiences

Shark Valley is a world of captivating wildlife. Guests can enjoy guided tram tours through beautiful landscapes. Look out for alligators and manatees as you go.
 
Bird watchers will find a paradise here. The park is full of different bird species.
 

Best Time to Visit

The best time to visit Everglades is from December to April. The weather is mild, and animals are more active. This makes it perfect for photography and exploration.
 

 

Check Rates For This Everglades

Air Boat Ride And Nature Walk

Crystal-clear waters and a vibrant coral reef teeming with marine life in Biscayne National Park

Essential Stop 2: Biscayne National Park

Biscayne National Park is a mix of adventure and natural beauty. It’s a great place to visit on your Florida Keys trip. The park’s vast marine ecosystem is perfect for outdoor fun.
 
You can enjoy the stunning views and learn about the park’s history at the visitor center.
 

Activities to Enjoy

At Biscayne National Park, there are many fun activities for everyone. Whether you love nature or seek excitement, this Florida Keys adventure is perfect for you. Here are some top activities:
 
Snorkeling: Explore vibrant coral reefs full of marine life.

Kayaking: Paddle through calm waters, finding hidden keys and waterways.

Hiking: Take scenic trails for amazing views and wildlife spotting.

Educational Tours: Join guided tours to learn about the park’s history and ecology.
 

 

Check Rates on this Biscayne Bay Jet Ski Tour

A colorful display of exotic fruits at Robert Is Here.

Essential Stop 3: Robert Is Here Fruit Stand

The Robert Is Here Fruit Stand is a highlight along the scenic drive. It’s known for its exotic tropical fruits and homemade smoothies. This vibrant spot is a must-see for anyone wanting to taste the Florida Keys’ unique flavors.
 
Visitors can try a variety of local produce, including starfruit, guava, and key lime pie.
 
The stand’s cheerful vibe captures the essence of the Florida Keys. It’s perfect for a refreshing break on your trip. Enjoy fresh fruit in a colorful setting that makes the Robert Is Here Fruit Stand a standout.
 

Chairs at the Florida Keys Visitor Center

Essential Stop 4: Florida Keys Visitor Center (Key Largo)

The Florida Keys Visitor Center is a key stop for travelers. It’s in Key Largo and packed with information. You’ll get maps, brochures, and expert advice to make your trip better.
 

Visitor Information and Tips

At the Florida Keys Visitor Center, you’ll find many helpful services. Here are some of the main ones:

Maps showing local spots and paths

Brochures with info on parks, beaches, and secret spots

Expert advice from staff on the best times to visit

Travel tips for Florida Keys to steer clear of common mistakes
 
If you’re looking for Key Largo info, this is the place. It offers insights into unique experiences, dining, and outdoor fun.
 

A snorkeler exploring coral reefs in the turquoise waters of John Pennekamp Coral Reef State Park

Essential Stop 5: John Pennekamp Coral Reef State Park

John Pennekamp Coral Reef State Park is the first underwater park in the United States. It’s located in the Florida Keys. This place is famous for its colorful coral reefs and diverse marine life. It’s a favorite spot for snorkeling and diving.
 

Snorkeling and Diving Adventures

At John Pennekamp Coral Reef, you can have amazing underwater experiences. The park offers guided tours to see the vibrant coral and different sea creatures. You can also rent gear on-site to explore the underwater world.

Guided snorkeling trips offer insights into the local ecosystem.

Beginner and advanced diving courses are available to cater to all skill levels.

Unique underwater features, including shipwrecks.
 
John Pennekamp Coral Reef State Park is perfect for both experienced divers and new snorkelers. It offers unforgettable adventures in Florida’s beautiful natural setting.
 

 

Check Rates On This Snorkeling And Sandbar Tour

The historic African Queen steamboat cruising through a serene Key Largo canal.

Essential Stop 6: African Queen Canal Cruise

Step aboard the African Queen Canal Cruise for a memorable ride. This famous boat, known from the 1951 film, shows off Key Largo’s canals. As you cruise, you’ll hear stories about the local plants and animals, and the area’s history.
 
This cruise is perfect for those who love history and nature. It moves slowly, letting you enjoy the calm views. You might see wildlife and learn about the special environment of the Florida Keys.
 
Perfect for families wanting to explore together.

Romantic option for couples looking to enjoy a peaceful experience.

Informative tours designed for all ages, making it accessible to everyone.

Boat tours in Florida Keys like he African Queen are a must-see on your Miami to Key West trip.
 

A lush, shaded trail surrounded by native tropical plants in Dagny Johnson Key Largo Hammock Botanical State Park

Essential Stop 7: Dagny Johnson Key Largo Hammock Botanical State Park

In the heart of Key Largo, Dagny Johnson Park is a peaceful retreat. It’s a hidden gem with Key Largo nature all around. The park has botanical gardens with native plants.
 
There are many hiking trails to explore. You’ll see tall trees and colorful plants everywhere.
 
Birdwatchers will love this place. It’s home to many bird species. Park staff can tell you all about the local wildlife.
 

A dolphin coming from the water during a show at Theater of the Sea.

Essential Stop 8: Theater of the Sea

The Theater of the Sea is a top spot in the Florida Keys.  Here, you can see marine life up close.
 
At the Theater of the Sea, you’ll see amazing marine shows. Dolphins and sea lions perform; it’s a great place for families and animal fans.
 
Want to get hands-on? You can swim with dolphins or join educational programs. Guided tours are also available. They teach you about the marine life and their homes.
 

Glide on a paddleboard through calm waters, spotting marine life below at Robbie's Marina in the Florida Keys

Essential Stop 9: Robbie’s Marina

Robbie’s Marina is a top spot for anyone visiting the Florida Keys. It offers a wide range of water sports and outdoor activities for all ages. The marina’s beautiful ocean view makes it perfect for both relaxation and adventure.
 

Fun Activities at Robbie’s

At Robbie’s Marina, you can enjoy many activities that highlight the Florida Keys’ beauty and fun. Here’s what awaits you:

Paddleboarding – Glide on a paddleboard through calm waters, spotting marine life below.

Kayaking – Paddle a kayak for a peaceful journey, ideal for nature lovers.

Boat Rentals – Rent a boat to explore nearby islands and hidden spots.

Feeding Tarpon – Feed tarpon at the marina for a memorable experience.

Shopping at Artisan Stands – Find unique crafts and souvenirs at local stands.
 

An exhibit of antique diving helmets and gear at the History of Diving Museum

Essential Stop 10: History of Diving Museum

The History of Diving Museum is in Islamorada’s heart. It’s a must-see for diving fans and history lovers. Here, you’ll find a vast collection of artifacts, photos, and stories. They show how diving has changed over time.
 
At the museum, you can see everything from old diving helmets to new scuba gear.  Here’s what they have:

Interactive exhibits that engage visitors of all ages

A stunning display of vintage diving equipment

Educational programs that provide insight into the science of diving

Illuminating stories about famous divers and pivotal moments in diving history
 
The museum is a top spot in the Florida Keys.
 

A beer at Islamorada Beer Company

Essential Stop 11: Islamorada Beer Company

Beer lovers will adore the Islamorada Beer Company. It’s a top spot in Florida for craft beer fans. Here, you can taste beers made right in the Florida Keys.
 
At the Islamorada Beer Company, you can enjoy craft beer tastings. They have a wide range of beers, from IPAs to stouts. The outdoor beer garden is perfect for relaxing and taking in the views.
 
The brewery also offers tours. On these tours, you’ll learn about how the beer is made. You’ll see how local ingredients add to the unique taste of their beers.
 
Make sure to visit the Islamorada Beer Company. It’s a great place to experience the craft beer scene in Islamorada and you’ll get to taste awesome beers.
 

A cozy outdoor seating area with colorful decor at Florida Keys Brewing Company

Essential Stop 12: Florida Keys Brewing Company

Looking for more drinks? The Florida Keys Brewing Company is a top spot for those wanting to taste local culture.
 
It’s located in the heart of the Keys. Here, they make unique local brews using fresh ingredients that show off the region’s beauty.
 

Local Craft Beer Tasting

At Florida Keys Brewing Company, you can explore a world of flavors. They offer tastings that let you try a variety of creative beers. You’ll find everything from tropical fruit-infused ales to unique twists on traditional styles.
 
Guided tours also let you see how the beer is made. You’ll learn about the brewing process and how your favorite beers are crafted. It’s a great way to appreciate the art of brewing while enjoying different samples.
 

Heading to the Florida Keys this year? 

 

Check out our must-have 7 day Florida Keys Itinerary!

 

Florida Keys Itinerary
The iconic giant lobster statue, Betsy, outside Rain Barrel Village art shops

Essential Stop 13: Rain Barrel Village

Rain Barrel Village is a must-see for Key West shoppers. It offers a lively atmosphere filled with local art and crafts. These pieces show off the creativity of local artisans.
 
As you explore, you’ll find shops with handmade jewelry, paintings, and unique souvenirs. Rain Barrel Village is a treasure trove of artistic displays.

Explore a variety of unique shops

Enjoy colorful sculptures and murals

Find special gifts and mementos
 
Whether you’re strolling or chatting with vendors, Rain Barrel Village is a must-stop for Key West shopping.
 

A stunning view of the Seven Mile Bridge stretching across turquoise waters

Essential Stop 14: Seven Mile Bridge (Views)

The Seven Mile Bridge is a stunning highlight on the Miami to Key West drive. It offers breathtaking views across the Atlantic Ocean. This iconic bridge connects several islands in the Florida Keys, making it a perfect spot for memorable photos.
 
The bridge also has a rich history. It was built in the early 1900s as part of the Overseas Railroad.
 

A peaceful shoreline with kayakers and mangroves at Curry Hammock State Park

Essential Stop 15: Curry Hammock State Park

Curry Hammock State Park is a gem in the Florida Keys. It offers stunning natural beauty and peaceful surroundings. Visitors can enjoy beautiful beaches and outdoor activities like hiking, birdwatching, and kayaking.
 
The park has trails that take you through mangroves. This is a great chance to see wildlife in its natural home. Kayaking lets you see the coastal ecosystem from a different view, perfect for water lovers.
 
Families and friends can have a relaxing day by the beach. The views and calm atmosphere make it a top spot in the Florida Keys.
 
Location: Florida Keys

Activities: Hiking, Birdwatching, Kayaking

Best Time to Visit: Year-round
 

A dolphin performing a jump during an interactive program at the Dolphin Research Center

Essential Stop 16: Dolphin Research Center

The Dolphin Research Center is in Grassy Key. It’s a top spot for those who love dolphins and marine life. Here, you can see trained dolphins up close. The center has programs for all ages to learn about these smart animals.
 

Interactive Dolphin Experiences

At the Dolphin Research Center, you’ll have amazing dolphin encounters. These experiences are both fun and educational.  Here you can:

Swim with dolphins

Participate in training sessions

Observe dolphin behaviors and interactions

 
This is a perfect stop for the family.
 

A picturesque white sand beach lined with palm trees at Sombrero Beach

Essential Stop 17: Sombrero Beach

Sombrero Beach is a top spot in the Florida Keys, known for its beautiful views and friendly vibe. It’s a favorite among families for its fun activities. It’s the ideal place for a sunny day.
 
The beach has soft, white sand perfect for laying out in the sun. There’s plenty of room to relax. You’ll find picnic spots, restrooms, and showers, making your visit comfortable.

Swimming in the clear waters is perfect, providing a refreshing break from the heat.

A wealth of water sports is available, from kayaking to paddleboarding.

Families can enjoy quality time together in picnic areas.
 
Sombrero Beach is a must-see for anyone visiting the Florida Keys. It offers a perfect mix of beauty and activities. Don’t miss out on this family-friendly beach for a day of sun and relaxation.
 

A view of the Old Bahia Honda Bridge framed by the crystal-clear waters of Bahia Honda State Park

Essential Stop 18: Bahia Honda State Park

Bahia Honda State Park is in the heart of the Florida Keys. It’s a top spot for nature lovers and beach fans. The park is known for its amazing beaches and stunning views. Visitors can enjoy the tropical beauty and try out many outdoor activities.
 

Best Beaches and Scenic Views

Bahia Honda State Park has some of the best beaches in Florida. It offers sandy shores perfect for swimming and picnics. For adventure, snorkeling in Bahia Honda shows off vibrant marine life and clear waters.

Calm Waters: Ideal for families and beginner snorkelers.

Natural Trails: Scenic paths weave through lush vegetation, providing stunning views of the coastline.

Wildlife Watching: Spotting opportunities for native birds and marine creatures.
 
Bahia Honda State Park is a highlight of the Florida Keys.
 

A freshwater pond surrounded by lush greenery, home to turtles and alligators, at Big Pine Key’s Blue Hole

Essential Stop 19: Big Pine Key’s Blue Hole

Big Pine Key’s Blue Hole is a must-see for those who love nature. This freshwater lake is in the heart of Big Pine Key. It’s home to many animals, including key deer, alligators, and birds.
 
There are hiking trails around the Blue Hole. These trails let you see wildlife up close. It’s a great place for photos and quiet moments, surrounded by nature.

Bring binoculars for optimal wildlife viewing.

Wear comfortable shoes for hiking along the trails.

Pack a picnic to enjoy the natural surroundings.
 
Don’t miss Big Pine Key’s Blue Hole on your Miami to Key West drive!
 

A close-up of a tiny Key deer standing among the mangroves in the National Key Deer Refuge

Essential Stop 20: National Key Deer Refuge

The National Key Deer Refuge gives you a special look at wildlife conservation. It’s all about saving the Key deer, a rare animal found in the Florida Keys. You can walk or drive through beautiful trails, enjoying the stunning views of the Keys.
 
Here’s what you can expect at the National Key Deer Refuge:

Feature Description
Wildlife Viewing Spot Key deer as they roam freely in their natural habitat.
Trails Walk or drive along well-maintained paths to enjoy scenic views.
Educational Programs Participate in guided tours and programs focused on conservation efforts.
Visitor Center Learn more about local wildlife and conservation through exhibits.

 

a blonde girl in a tie dye shirt holding a picture of beer and another picture of a tropical mixed drink

Essential Stop 21: No Name Pub

No Name Pub is a true gem in the Florida Keys dining world. It opened in the 1930’s and has been a favorite spot ever since. It welcomes both locals and visitors with its unique charm and relaxed atmosphere.
 
Guests love the seafood dishes that celebrate the Keys’ fishing traditions. The key lime pie is a big hit, offering a sweet taste of the tropics.
 
The pub’s decor is full of quirky touches, like dollar bills from past visitors. Friendly service makes No Name Pub a top choice for food lovers.
 
Whether you’re in for a quick snack or a bigger meal, No Name Pub is perfect for Florida Keys casual dining.
 

The iconic Southernmost Point Buoy painted in vibrant colors marking the southernmost spot in the continental U.S.

Essential Stop 22: Southernmost Point Buoy

The Southernmost Point Buoy is a key landmark in Key West. It marks the southernmost tip of the continental United States. Visitors from all over come to take photos against its bright colors.
 
It’s near a lively area with murals and shops. Here, travelers can explore and take amazing photos. It’s a great spot to capture a memorable moment in Key West.
 

A lively scene of street performers and tourists enjoying the sunset celebration at Mallory Square

Essential Stop 23: Mallory Square

Mallory Square is a lively spot for evening fun in Key West. Every night, it turns into a bustling place for the famous Key West sunset celebration. People come to see the beautiful sunset and enjoy different entertainment.
 
The square is filled with energy, thanks to local street performers. They do amazing acts like fire juggling and playing music. Food stalls offer tasty local dishes, letting visitors taste the Florida Keys’ flavors.
 

The historic Ernest Hemingway Home

Essential Stop 24: Ernest Hemingway Home and Museum

The Ernest Hemingway museum is a tribute to the famous American author. It’s located in Key West’s heart, offering a deep dive into Hemingway’s life and writing. Visitors can take guided tours to learn about his creative process and the landscapes that inspired him.
 
The museum’s gardens are as beautiful as they are historic. They reflect the calm that influenced Hemingway’s writing. Guests can walk through, enjoying the views and meeting the famous six-toed cats. These cats are Hemingway’s pets’ descendants.
 

Learn more about the Ernest Hemingway home and museum here!

 

beach at Fort Zachary Taylor Historic State Park overlooking the ocean

Essential Stop 25: Fort Zachary Taylor Historic State Park

Fort Zachary Taylor is a key spot in Florida history, especially during the Civil War. It lets visitors explore the past while enjoying Key West’s stunning coast. This historic park is a mix of history and natural beauty.
 

Historic Sites to Explore

At Fort Zachary Taylor, you can take part in activities that show its historical importance. The park also has exhibits with artifacts and info on Florida’s Civil War history.
 
The park also has a lovely beach for swimming, picnics, and chilling out. This blend of fun and learning makes Fort Zachary Taylor a top spot in Key West.
 

Conclusion

The Miami to Key West drive is an experience that shows off the essence of the Florida Keys. Each stop, from the Seven Mile Bridge to the Ernest Hemingway Home, is a must-stop on your adventure.
 
Planning your trip well makes it even better. This drive summary highlights the natural beauty and history. It’s key to have a good plan for your Florida Keys adventure.
 
Safe travels!
 

Heading to the Florida Keys this year? 

 

Check out our must-have 7 day Florida Keys Itinerary!

 

Florida Keys Itinerary

Booking a last-minute trip to Florida?  

If so, we have you covered.  Here are some top recommended tours and experiences!

Top Tours in Florida – Viator 

Top Hotels In Florida – Booking.com

 Looking To Get Around In Florida

Check out rental car rates here! 🚗