Last Updated on March 31, 2024

Looking for the most romantic and relaxing adults-only hotel in Key West?  Look no further! 

Key West has always been a popular destination in Florida because of its amazing beaches, vibrant nightlife, rich history, and endless activities.

Aside from that, Key West also offers the best child-free accommodations for those who want to escape from the hustle and bustle of life and work.

I’m a Florida travel expert and in this post, we have compiled the best hotels for adults in Key West that are perfect for couples and individuals who want to enjoy a satisfying stay in the sunny city of Key West. 

Here’s our list of the best adult-only hotel options in Key West that you might want to consider.

The Best Key West Adults-Only Hotels! 

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The Cabana Inn Key West - adult exclusive features a nicely kept conch house design, an outdoor swimming pool, and a hot tub, where guests can unwind and enjoy the warm Florida sunshine.

⭐️ Rating 8.0/10 with over 662 reviews!

Located in Downtown Key West, The Cabana Inn is the perfect place for everyone who wants a tropical and relaxing vacation. 

This adult-exclusive inn features a nicely kept conch house design, an outdoor swimming pool, and a hot tub, where guests can unwind and enjoy the warm Florida sunshine.  

With its best location situated in the middle of historic Duval Street, it provides easy access to famous landmarks in Key West and is a short walk, only about 0.5 km, from the Ernest Hemingway Home and Museum. 

The spacious and comfy rooms, with a nice touch of wooden floors and high ceilings, make this place extra special. 

They also serve continental breakfast daily to start off your day and a happy hour to enjoy some drinks between 5-7pm. 

Address: 413 Appelrouth Lane, Downtown Key West, FL 

Here’s what a past guest said about this hotel:

Our 2nd time staying!!! Patrick was welcoming from the start!!! always a min to chat anytime we saw one another!! location is just far enough from the hustle bustle but close enough to everything!! oh and the 4 am rooster wake up was a plus.


David_United States 




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The Anna Maria Island Beach View 209 features modern amenities, including a fully equipped kitchen, a spacious living area, and a private balcony where guests can unwind and soak in the breathtaking ocean vistas.

⭐️ Rating 8.7/10 with over 1226 reviews!

Situated at the heart of Key West, L’Habitation Guesthouse offers the most relaxing and exclusive stay in the vibrant city of Key West, Florida. 

This guesthouse features quality accommodations with cozy rooms, spacious bathrooms, and comfy large-sized beds.

They also have a beautiful garden and terrace where you can chill out and unwind. 

In the morning, don’t forget to enjoy the delicious continental breakfast served with pastries and coffee.  

You can also partake in the happy hour during afternoons and indulge yourself with some cocktails and any beverage of your choice. 

Depending on your mood, you can explore some Key West gems such as the Mallory Dock, Key West Aquarium, and Jackson Square are just a few blocks away from the property. 

Address: 408 Eaton Street, Downtown Key West, FL 

Here’s what a past guest said about this hotel:

The room was large with a king size bed. We had a porch out back with trees to provide shade so we could sit outside. The place was 3 blocks from Duval street so easy to walk to and close enough to walk to Malory Square. My wife wants to stay there again.


Ron_United States 




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The Anna Maria Island Beach Palms 6B in Bradenton Beach offers a delightful beachfront escape for travelers seeking relaxation and tranquility.

⭐️ Rating 8.5/10 with over 481 reviews!

The Paradise Inn is indeed a paradise for couples and individuals who want to enjoy a relaxing and top-notch accommodations in Key West. 

This inn offers beautifully designed landscapes and gardens that provide a serene and tranquil atmosphere.  

Also, the clean white interiors and design give a bright and tranquil ambiance to the property. 

Guests can enjoy a complimentary breakfast and amenities including a stellar pool area and an outdoor hot tub for a more fun and memorable experience. 

The Key West Museum is just a 15-minute walk away. If you want to visit the beach, the nearest one is the Higgs Beach which is just a 5 minute drive from the property. 

Address: 819 Simonton Street, Downtown Key West, FL 

Here’s what a past guest said about this hotel:

Breakfast was great, location was great and it was so beautiful in and out. Foster is the most kindest and amazing person we could ever meet and made our stay at paradise inn even better. Thank you so much.


Ashley_United Kingdom 




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Guests can also take advantage of Coquina Beach Club 110's outdoor swimming pool and barbecue area for outdoor enjoyment.

⭐️ Rating 7.4/10 with over 1223 reviews!

Southernmost Inn is a private splurge with an excellent location and just a skip away from the local beach. 

The setting oozes a unique tropical theme in each room that makes you feel like you’ve stepped into your own private paradise. 

This inn features 2 heated outdoor pools and a hot tub where guests can relax and soak up under the sun. 

In addition, they also have a fitness center, a large outdoor patio and a sun deck for a more relaxing and enjoyable stay. 

A continental breakfast is served each morning to kickstart your day before you go out and explore nearby attractions such as the Key West Butterfly and Nature Conservatory, and the Ernest Hemingway Museum. 

Address: 525 United Street, Downtown Key West, FL

Here’s what a past guest said about this hotel:

The whole Inn was absolutely amazing. Beautiful room and furniture. King size bed with a great mattress. The pool was great and the breakfast was more than I could have imagined. So much to choose from. What a little diamond in Key West. I will definately be staying here again next year.






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Guests can enjoy the outdoor patio and barbecue area, perfect for al fresco dining and entertaining at Street South House #54586

⭐️ Rating 8.5/10 with over 174 external reviews!

A few minutes walk away from Duval Street is this modern boutique hotel, Kimpton Ridley House.

The place offers a laid-back accommodation, giving you a private home guest feels more than any typical hotel. 

Each room has spacious balconies with a bright and beachy feel and beautifully decorated interiors. 

Don’t forget to soak in the pool and enjoy some cocktails and frozen drinks during your stay. 

With an excellent location, popular attractions are just nearby the property including the Mallory Square, Key West Aquarium, and other must-visit Key West, Florida museums. 

Address: 601 Caroline Street, Downtown Key West, FL

Here’s what a past guest said about this hotel:

Staff was exceptionally welcoming and helpful. Room was spotless, spacious, and comfortable. One block away from Duval St and real close to all the other attractions. Free bike rental was a great added bonus


Peter_United States 




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An Island Getaway at Palm Tree Villas in Holmes Beach is a dream destination for those seeking a tropical escape. This exquisite vacation rental offers a serene and peaceful atmosphere, nestled among lush palm trees.

⭐️ Rating 8.6/10 with over 492 reviews!

Another top-rated adult-only accommodation in Downtown Key West, La Pension Inn, feels like a home. 

This bed and breakfast inn offers a daily continental breakfast and a fantastic outdoor pool for you to enjoy. 

In addition to the feel-at-home vibe are the complete home facilities, daily cleaning services, and daily newspaper perks. 

The front porch with garden views also gives a nice touch to the property. 

With an excellent location just a walking distance away from the old town center, you can visit the Hemingway House and other nearby restaurants and shops. 

Address: 809 Truman Avenue, Downtown Key West, FL 

Here’s what a past guest said about this hotel:

Great location. Walking distance to everything. Nice Continental breakfast at sister location across street. Free parking. Big room, big bathroom, comfortable king size bed, AC works great, great front porch with rockers, friendly staff!


Tracy_United States




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Alamanda Villa on Holmes Beach is a hidden gem that offers an enchanting tropical escape. Situated on Anna Maria Island, this vacation rental provides a luxurious and secluded retreat for travelers seeking relaxation and tranquility.

⭐️ Rating 9.4/10 with over 411 reviews!

Located 200 meters away from Duval Street is H20 Suites, a modern luxury suite with plenty of complimentary amenities and facilities for each guest to enjoy. 

The tropical modern-infused design and the stellar rooftop pool area make this property stand out compared to other adults-only accommodations in Key West.  

Each room provides spacious and bright interiors, with state-of-the-art technology, and a nice couch to sit back while enjoying the tropical view of the front yard. 

Other rooms also offer a private pool, perfect for couples who want a more exclusive and romantic experience. 

They have an on-site bar available for those who want to enjoy a drink or two.

They also bike hire options if you want to explore the other parts of Key West in a bicycle. 

Address: 1212 Simonton Street, Downtown Key West, FL 

Here’s what a past guest said about this hotel:

“The plunge pool and the privacy offered really allowed us to relax, be together and get some well deserved alone time. It’s proximity to Duval street and other key locations makes it a great hub for your stay. The staff was nice but Lee was the absolute best of them all! She’s amazing and oozes positive vibes and that made our stay just that much better! 






Photo Credit- Key West Harbor Inn

Waterline Marina Resort & Beach Club, Autograph Collection in Holmes Beach is a luxurious waterfront haven that embodies elegance and coastal charm

⭐️ Rating 9.3/10 with over 403 reviews!

Another Key West icon, the Key West Harbor Inn is ideal for those who want to relax in a serene and secluded area.

With an excellent location close to Key West’s local attractions and beaches, this property is popular a popular area for visitors who want to enjoy activities such as snorkeling and cycling.  

They also feature an outdoor pool and beautiful garden views for everyone to unwind, and a balcony to enjoy ocean views making them ideal for enjoying Key West sunset. 

The rooms are clean and spacious, with private bathrooms and showers. The best part is they also offer facilities for guests with disabilities. 

Address: 219 Elizabeth Street, Downtown Key West, FL 

Here’s what a past guest said about this motel:

The small B&B seems to be in the middle of rainforest, love the location each widow was on palm tree crown. Great location and free drink for happy hour 4″30-5:30


Cezarina_United States 




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The Anna Maria Island Beach Paradise 5 in Holmes Beach offers a perfect blend of luxury and relaxation, just steps away from the pristine shores of Anna Maria Island.

⭐️ Rating 8.3/10 with over 267 reviews!

The rainbow flags exterior of this gay male adult-only guesthouse in the historic Duval Street screams that you’re in for a special stay. 

Located above Bourbon Street Pub, New Orleans House offers a vibrant and welcoming atmosphere for male LGBTQ+ travelers in Key West, Florida. 

This guest house features an on-site bar and restaurant, an outdoor pool, and a sundeck where you can chill out and enjoy some drinks and music for a vibrant stay in Key West. 

In addition, complimentary breakfast and happy hour are available for all guests.

They also have a fitness center for those who want to lift weights and workout. 

Address: 724 Duval Street, Downtown Key West, FL

Here’s what a past guest said about this motel:

New Orleans house is a great place. It’s conveniently located to just about everything. The staff is wonderful. The facility is top notch. We love it there! Highly recommend booking your next vacation with them.


Brian_United States 




Photo Credit- Alexander’s Gay and Lesbian Guesthouse

Guests can relax by the private pool, soak in the sunshine on the sundeck on Blue Wave Villa West

⭐️ Rating 9.6/10 with over 42 reviews!

Another unique stay in Key West is the 3-story conch-style house exclusive for gays and lesbians, the Alexander’s Gay Lesbian Guesthouse. 

Each room features a flat-screen television, a private bathroom, and a wardrobe.  

Also, one thing to love about this place is the outdoor pool and on-site bar where guests can hang out and experience a cocktail night with fellow LGBTQ+ guests. 

In the morning, a delicious continental breakfast is served at the poolside while reading a book from the property’s on-site library. 

Address: 1118 Fleming Street, Downtown Key West, FL 

Here’s what a past guest said about this apartment:

Everything about it was great! Food was fantastic! Atmosphere, staff, facilities, room, etc was better than I expected. I already reserved the same room for next year as this will be an annual trip for me.


Liscio_United States 




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Nautilus 105 in Anna Maria is a captivating vacation rental that promises a truly enchanting island experience

⭐️ Rating 9.5/10 with over 122 reviews!

In this adults-only hotel, you get to enjoy two outdoor pools, a private balcony, and plenty of amenities. 

You can choose different types of rooms depending on the vibe that you are looking for.

From cottages to master suites, all of which have access to all facilities including a flat-screen TV and a refrigerator. 

On Sundays, you can enjoy a romantic night with live jazz music and cocktails while enjoying the garden views. 

With a great setting just a 1-minute walk away from Duval Street and other famous attractions in the city, you will never get tired of all the activity opportunities nearby. 

Definitely one of the nicest places I can recommend in Key West for a romantic weekend. 

Address: 526 Angela Street, Downtown Key West, FL 

Here’s what a past guest said about this hotel:

The grounds were absolutely breathtaking. The details in which the staff took care of us, especially Richard the bartender and Ray at front desk. We were on our honeymoon and it couldn’t have been more magical. Wonderful location too!


Kelsey_United States 



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Palm trees and beach scene in Smathers Beach Key West Florida

Frequently Asked Questions – Key West Adults Only Hotels 


What Does Adults-Only Hotel Mean? 

An adults-only hotel is a type of accommodation that exclusively caters to guests ages 18 years old and above. 

These hotels are specifically designed for adults, providing an environment tailored to their preferences and needs. 

What To Expect At An Adults-Only Resort? 

At an adults-only resort, you can expect a relaxing and peaceful atmosphere designed for adults to enjoy a vacation where you can truly unwind and escape from everyday life. 

What Is A Couples-Only Resort? 

A couples-only resort is also known as an adult-only resort, designed for adults and couples who want to enjoy a stress-free vacation or an exclusive honeymoon away from the children (if you have one). 

Is Key West Fun For Couples? 

Absolutely!  Key West is a great place for a perfect and romantic getaway for couples, where they can enjoy different activities, stunning beaches, and romantic sunsets. 

Key West offers plenty of opportunities for couples to create a memorable vacation. 



Best Key West Adults-Only Hotels in 2023

Final Thoughts: Best Key West Adults-Only Hotels 

When it comes to finding the perfect adults-only hotel in Key West, there’s no doubt there are plenty to choose from. 

Whether you’re looking for a romantic and laid-back getaway or a fun spot to meet new people, Key West offers a variety of accommodations that cater to your preference and needs. 

Several of these hotels have amenities such as free breakfast, free wifi, room service, cable channels, and even offer watersports.  Be sure to check the individual hotel page for all of their amenities. 

So, check out these best 11 adults-only hotels in the city of Key West and finally book your stay! 



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Booking a last-minute trip to Key West?  

If so, we have you covered.  Here are some top recommended tours and hotels!

Top Tours in Key West

Key West Sunset Sail (With Full Bar, Live Music, and Hors D’oeuvres)

Key West Reef Snorkeling Excursion (Half-Day Snorkeling Tour In Key West Florida)

Key West Mangrove Kayak Eco Tour (Kayak Tour Of Key West Mangroves)

Key West Sunset Dinner Cruise (With Tropical Dinner Buffet!)

Looking To Get Around In Key West Florida

Check out rental car rates here! 🚗